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Identification of DES1 as a Vitamin A Isomerase in Müller Glial Cells of the Retina

Absorption of a light particle by an opsin-pigment causes photoisomerization of its retinaldehyde chromophore. Restoration of light sensitivity to the resulting apo-opsin requires chemical re-isomerization of the photobleached chromophore. This is carried out by a multistep enzyme pathway called the...

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Detalles Bibliográficos
Autores principales: Kaylor, Joanna J., Yuan, Quan, Cook, Jeremy, Sarfare, Shanta, Makshanoff, Jacob, Miu, Anh, Kim, Anita, Kim, Paul, Habib, Samer, Roybal, C. Nathaniel, Xu, Tongzhou, Nusinowitz, Steven, Travis, Gabriel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522777/
https://www.ncbi.nlm.nih.gov/pubmed/23143414
http://dx.doi.org/10.1038/nchembio.1114