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Identification of DES1 as a Vitamin A Isomerase in Müller Glial Cells of the Retina
Absorption of a light particle by an opsin-pigment causes photoisomerization of its retinaldehyde chromophore. Restoration of light sensitivity to the resulting apo-opsin requires chemical re-isomerization of the photobleached chromophore. This is carried out by a multistep enzyme pathway called the...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522777/ https://www.ncbi.nlm.nih.gov/pubmed/23143414 http://dx.doi.org/10.1038/nchembio.1114 |