Active site profiling reveals coupling between domains in SRC-family kinases

Protein kinases, key regulators of intracellular signal transduction, have emerged as an important class of drug targets. Chemical proteomic tools that facilitate the functional interrogation of protein kinase active sites are powerful reagents for studying the regulation of this large enzyme family...

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Detalles Bibliográficos
Autores principales: Krishnamurty, Ratika, Brigham, Jennifer L., Leonard, Stephen E., Ranjitkar, Pratistha, Larson, Eric T., Dale, Edward J., Merritt, Ethan A., Maly, Dustin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522794/
https://www.ncbi.nlm.nih.gov/pubmed/23143416
http://dx.doi.org/10.1038/nchembio.1118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522794/
https://www.ncbi.nlm.nih.gov/pubmed/23143416
http://dx.doi.org/10.1038/nchembio.1118

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