The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole

Bacterial invasion results in the rapid induction of an acute state of cytosolic amino acid (AA) starvation, provoked by host membrane damage. Bacteria-induced AA starvation, in turn, down-regulates mTOR signaling while triggering autophagy and the integrated stress response pathway dependent on GCN...

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Detalles Bibliográficos
Autores principales: Tattoli, Ivan, Philpott, Dana J., Girardin, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522883/
https://www.ncbi.nlm.nih.gov/pubmed/23259056
http://dx.doi.org/10.1242/bio.20122840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522883/
https://www.ncbi.nlm.nih.gov/pubmed/23259056
http://dx.doi.org/10.1242/bio.20122840

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