Cargando…
The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole
Bacterial invasion results in the rapid induction of an acute state of cytosolic amino acid (AA) starvation, provoked by host membrane damage. Bacteria-induced AA starvation, in turn, down-regulates mTOR signaling while triggering autophagy and the integrated stress response pathway dependent on GCN...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522883/ https://www.ncbi.nlm.nih.gov/pubmed/23259056 http://dx.doi.org/10.1242/bio.20122840 |