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Hedgehog pathway inhibitors – current status and future prospects

The Hedgehog (Hh) proteins comprise a group of secreted proteins that regulate cell growth, differentiation and survival. Inappropriate activation of the Hh signaling pathway has been implicated in the development of a variety of cancers. Hedgehog pathway inhibitors are a relatively new class of the...

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Detalles Bibliográficos
Autores principales: Sheikh, Asfandyar, Alvi, Arsalan Ahmad, Aslam, Hafiz Muhammad, Haseeb, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523044/
https://www.ncbi.nlm.nih.gov/pubmed/23116301
http://dx.doi.org/10.1186/1750-9378-7-29