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Lubiprostone stimulates small intestinal mucin release

BACKGROUND: Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE(1)) used for chronic constipation. The best known action of lubiprostone is simulation of Cl(-) dependent fluid secretion. In a mouse model of the genetic disease cystic fibrosis, we previously showed tha...

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Detalles Bibliográficos
Autor principal: De Lisle, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523065/
https://www.ncbi.nlm.nih.gov/pubmed/23130661
http://dx.doi.org/10.1186/1471-230X-12-156