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Lubiprostone stimulates small intestinal mucin release
BACKGROUND: Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE(1)) used for chronic constipation. The best known action of lubiprostone is simulation of Cl(-) dependent fluid secretion. In a mouse model of the genetic disease cystic fibrosis, we previously showed tha...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523065/ https://www.ncbi.nlm.nih.gov/pubmed/23130661 http://dx.doi.org/10.1186/1471-230X-12-156 |