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Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese population

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is an escalating medical problem worldwide. A nonsynonymous single nucleotide polymorphism rs738409 (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) predisposes susceptibility to NAFLD; however, its association with steat...

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Detalles Bibliográficos
Autores principales: Li, Yiling, Xing, Chao, Tian, Zhong, Ku, Hung-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523076/
https://www.ncbi.nlm.nih.gov/pubmed/23176674
http://dx.doi.org/10.1186/1471-2350-13-113