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Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese population
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is an escalating medical problem worldwide. A nonsynonymous single nucleotide polymorphism rs738409 (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) predisposes susceptibility to NAFLD; however, its association with steat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523076/ https://www.ncbi.nlm.nih.gov/pubmed/23176674 http://dx.doi.org/10.1186/1471-2350-13-113 |