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Herb-Drug Interaction of Paullinia cupana (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats

Paullinia cupana is used in weight-loss programs as a constituent of medicinal/dietary supplements. This study aimed to assess a potential herb-drug interaction among a standardized (certified) Paullinia cupana extract and amiodarone (narrow therapeutic index drug) in rats. In a first pharmacokineti...

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Detalles Bibliográficos
Autores principales: Rodrigues, Márcio, Alves, Gilberto, Lourenço, Nulita, Falcão, Amílcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523151/
https://www.ncbi.nlm.nih.gov/pubmed/23304200
http://dx.doi.org/10.1155/2012/428560