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Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson’s disease

BACKGROUND: Retinoic acid (RA) is a biologically active derivative of vitamin A. Previous studies have demonstrated that RA has protective effects against damage caused by H(2)O(2) or oxygen-glucose deprivation in mesangial and PC12 cells. Pretreatment with 9-cis-retinoic acid (9cRA) reduced infarct...

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Detalles Bibliográficos
Autores principales: Yin, Lian-Hu, Shen, Hui, Diaz-Ruiz, Oscar, Bäckman, Cristina M, Bae, Eunkyung, Yu, Seong-Jin, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523975/
https://www.ncbi.nlm.nih.gov/pubmed/23040108
http://dx.doi.org/10.1186/1471-2202-13-120