IGF2/H19 hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome

BACKGROUND: Silver-Russell syndrome (SRS) is characterized by severe intrauterine and postnatal growth failure and frequent body asymmetry. Half of the patients with SRS carry a DNA hypomethylation of the imprinting center region 1 (ICR1) of the insulin-like growth factor 2 (IGF2)/H19 locus, and the...

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Detalles Bibliográficos
Autores principales: Kannenberg, Kai, Weber, Karin, Binder, Cathrin, Urban, Christina, Kirschner, Hans-Joachim, Binder, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523983/
https://www.ncbi.nlm.nih.gov/pubmed/22989232
http://dx.doi.org/10.1186/1868-7083-4-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523983/
https://www.ncbi.nlm.nih.gov/pubmed/22989232
http://dx.doi.org/10.1186/1868-7083-4-15

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