Cargando…

Mathematical modeling of left ventricular dimensional changes in mice during aging

Cardiac aging is characterized by diastolic dysfunction of the left ventricle (LV), which is due in part to increased LV wall stiffness. In the diastolic phase, myocytes are relaxed and extracellular matrix (ECM) is a critical determinant to the changes of LV wall stiffness. To evaluate the effects...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Tianyi, Chiao, Ying Ann, Wang, Yunji, Voorhees, Andrew, Han, Hai-Chao, Lindsey, Merry L, Jin, Yu-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524011/
https://www.ncbi.nlm.nih.gov/pubmed/23281647
http://dx.doi.org/10.1186/1752-0509-6-S3-S10