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Mathematical modeling of left ventricular dimensional changes in mice during aging
Cardiac aging is characterized by diastolic dysfunction of the left ventricle (LV), which is due in part to increased LV wall stiffness. In the diastolic phase, myocytes are relaxed and extracellular matrix (ECM) is a critical determinant to the changes of LV wall stiffness. To evaluate the effects...
Autores principales: | Yang, Tianyi, Chiao, Ying Ann, Wang, Yunji, Voorhees, Andrew, Han, Hai-Chao, Lindsey, Merry L, Jin, Yu-Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524011/ https://www.ncbi.nlm.nih.gov/pubmed/23281647 http://dx.doi.org/10.1186/1752-0509-6-S3-S10 |
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