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PAI-1 and t-PA/PAI-1 complex potential markers of fibrinolytic bleeding after cardiac surgery employing cardiopulmonary bypass

BACKGROUND: Enhanced bleeding remains a serious problem after cardiac surgery, and fibrinolysis is often involved. We speculate that lower plasma concentrations of plasminogen activator inhibitor – 1 (PAI-1) preoperatively and tissue plasminogen activator/PAI-1 (t-PA/PAI-1) complex postoperatively m...

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Detalles Bibliográficos
Autores principales: Ozolina, Agnese, Strike, Eva, Jaunalksne, Inta, Krumina, Angelika, Bjertnaes, Lars J, Vanags, Indulis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524048/
https://www.ncbi.nlm.nih.gov/pubmed/23110524
http://dx.doi.org/10.1186/1471-2253-12-27