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Regulation of Endogenous Glucose Production in Glucose Transporter 4 Over-Expressing Mice

Strategies to amplify whole-body glucose disposal are key therapies to treat type 2 diabetes. Mice that over-express glucose transporter 4 (Glut4) in skeletal muscle, heart, and adipose tissue (G4Tg) exhibit increased fasting glucose disposal and thus lowered blood glucose. Intriguingly, G4Tg mice a...

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Detalles Bibliográficos
Autores principales: Berglund, Eric D., Li, Candice Y., Ayala, Julio E., McGuinness, Owen P., Wasserman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524103/
https://www.ncbi.nlm.nih.gov/pubmed/23285006
http://dx.doi.org/10.1371/journal.pone.0052355