Tumor Development, Growth Characteristics and Spectrum of Genetic Aberrations in the TH-MYCN Mouse Model of Neuroblastoma

BACKGROUND: The TH-MYCN transgenic neuroblastoma model, with targeted MYCN expression to the developing neural crest, has been used to study neuroblastoma development and evaluate novel targeted tumor therapies. METHODS: We followed tumor development in 395 TH-MYCN (129X1/SvJ) mice (125 negative, 20...

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Detalles Bibliográficos
Autores principales: Rasmuson, Agnes, Segerström, Lova, Nethander, Maria, Finnman, Jennie, Elfman, Lotta H. M., Javanmardi, Niloufar, Nilsson, Staffan, Johnsen, John Inge, Martinsson, Tommy, Kogner, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524187/
https://www.ncbi.nlm.nih.gov/pubmed/23284678
http://dx.doi.org/10.1371/journal.pone.0051297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524187/
https://www.ncbi.nlm.nih.gov/pubmed/23284678
http://dx.doi.org/10.1371/journal.pone.0051297

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