Expression and Activity of Fyn Mediate Proliferation and Blastic Features of Chronic Myelogenous Leukemia

The BCR-ABL1 oncogene is a tyrosine kinase that activates many signaling pathways, resulting in the induction of chronic myeloid leukemia (CML). Kinase inhibitors, such as imatinib, have been developed for the treatment of CML; however, the terminal, blast crisis phase of the disease remains a clini...

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Detalles Bibliográficos
Autores principales: Singh, Melissa M., Howard, Adrienne, Irwin, Mary E., Gao, Yin, Lu, Xiaolin, Multani, Asha, Chandra, Joya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524192/
https://www.ncbi.nlm.nih.gov/pubmed/23284724
http://dx.doi.org/10.1371/journal.pone.0051611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524192/
https://www.ncbi.nlm.nih.gov/pubmed/23284724
http://dx.doi.org/10.1371/journal.pone.0051611

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