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Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma

Glioma includes astrocytoma, oligodendroglioma, ependymoma and glioblastoma. We previously reported the epigenetic silencing of paternally expressed gene 3 (PEG3) in glioma cell lines. In this study, we investigated methylation of an exonic CpG island in the promoter region and the expression of PEG...

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Detalles Bibliográficos
Autores principales: Otsuka, Susumu, Maegawa, Shinji, Takamura, Ayumi, Kamitani, Hideki, Watanabe, Takashi, Oshimura, Mitsuo, Nanba, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524298/
https://www.ncbi.nlm.nih.gov/pubmed/19367087
http://dx.doi.org/10.2183/pjab.85.157