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Discovery of α-Klotho unveiled new insights into calcium and phosphate homeostasis
α-Klotho was first identified as the responsible gene in a mutant mouse line whose disruption results in a variety of premature aging-related phenotypes. α-Klotho has been shown to participate in the regulation of parathyroid hormone secretion and trans-epithelial transport of Ca(2+) in the choroid...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japan Academy
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524302/ https://www.ncbi.nlm.nih.gov/pubmed/19282648 http://dx.doi.org/10.2183/pjab/85.125 |