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Effect of Small Hairpin RNA Targeting Endothelin-Converting Enzyme-1 in Monocrotaline-Induced Pulmonary Hypertensive Rats

The purpose of this study was to investigate the therapeutic effects of small hairpin RNA (shRNA) targeting endothelin-converting enzyme (ECE)-1 in monocrotaline (MCT)-induced pulmonary hypertensive rats. Ninty-four Sprague-Dawley rats were divided into three groups: control (n = 24), MCT (n = 35) a...

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Detalles Bibliográficos
Autores principales: Son, Jae Sung, Kim, Kwan Chang, Kim, Bo Kyung, Cho, Min-Sun, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524430/
https://www.ncbi.nlm.nih.gov/pubmed/23255850
http://dx.doi.org/10.3346/jkms.2012.27.12.1507