Nanoparticles for Improved Local Retention after Intra-Articular Injection into the Knee Joint

PURPOSE: To evaluate using cationic polymeric nanoparticles that interact with hyaluronate to form ionically cross-linked hydrogels to increase the intra-articular retention time of osteoarthritis drugs in the synovial cavity. METHODS: In vitro tests included nanoparticle release from cross-linked h...

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Detalles Bibliográficos
Autores principales: Morgen, Michael, Tung, David, Boras, Britton, Miller, Warren, Malfait, Anne-Marie, Tortorella, Micky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524502/
https://www.ncbi.nlm.nih.gov/pubmed/22996566
http://dx.doi.org/10.1007/s11095-012-0870-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524502/
https://www.ncbi.nlm.nih.gov/pubmed/22996566
http://dx.doi.org/10.1007/s11095-012-0870-x

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