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Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells

DNA cytosine methylation (5mC) is indispensable for a number of cellular processes, including retrotransposon silencing, genomic imprinting, and X chromosome inactivation in mammalian development. Recent studies have focused on 5-hydroxymethylcytosine (5hmC), a new epigenetic mark or intermediate in...

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Detalles Bibliográficos
Autores principales: Kubiura, Musashi, Okano, Masaki, Kimura, Hiroshi, Kawamura, Fumihiko, Tada, Masako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524505/
https://www.ncbi.nlm.nih.gov/pubmed/23111490
http://dx.doi.org/10.1007/s10577-012-9317-9