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Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation

Mitochondria are highly motile organelles that constantly undergo fission and fusion. Impairment of mitochondrial dynamics is associated with mitochondrial dysfunction and is frequently linked to the pathogenesis of neurodegenerative diseases and cancer. We have previously shown that biallelic inact...

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Detalles Bibliográficos
Autores principales: Lin, H-Y, Lai, R-H, Lin, S-T, Lin, R-C, Wang, M-J, Lin, C-C, Lee, H-C, Wang, F-F, Chen, J-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524647/
https://www.ncbi.nlm.nih.gov/pubmed/22955947
http://dx.doi.org/10.1038/cdd.2012.106