SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells

BACKGROUND: FLT3-ITD and FLT3-TKD mutations are frequently found in acute myeloid leukemia (AML). This makes tyrosine kinase FLT3 a highly attractive target for therapeutic drug development. However, effective drugs have not yet emerged. This study is intended to identify and to characterize new FLT...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yao, Chen, Yun, Xu, Xuesong, Fu, Xueqi, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524753/
https://www.ncbi.nlm.nih.gov/pubmed/23216927
http://dx.doi.org/10.1186/1756-8722-5-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524753/
https://www.ncbi.nlm.nih.gov/pubmed/23216927
http://dx.doi.org/10.1186/1756-8722-5-72

Ejemplares similares