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SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells

BACKGROUND: FLT3-ITD and FLT3-TKD mutations are frequently found in acute myeloid leukemia (AML). This makes tyrosine kinase FLT3 a highly attractive target for therapeutic drug development. However, effective drugs have not yet emerged. This study is intended to identify and to characterize new FLT...

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Detalles Bibliográficos
Autores principales:	Guo, Yao, Chen, Yun, Xu, Xuesong, Fu, Xueqi, Zhao, Zhizhuang Joe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524753/ https://www.ncbi.nlm.nih.gov/pubmed/23216927 http://dx.doi.org/10.1186/1756-8722-5-72

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