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Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum
The coexistence of multiple independently circulating strains in pathogen populations that undergo sexual recombination is a central question of epidemiology with profound implications for control. An agent-based model is developed that extends earlier ‘strain theory’ by addressing the var gene fami...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524794/ https://www.ncbi.nlm.nih.gov/pubmed/23251784 http://dx.doi.org/10.7554/eLife.00093 |