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Virtual screening of plant derived compounds for aldose reductase inhibition using molecular docking

The role of the aldose reductase in type 2 diabetes is widely described. Therefore, it is of interest to identify plant derived compounds to inhibit its activity. We studied the protein-ligand interaction of 267 compounds from different parts of seven plants (Allium sativum, Coriandrum sativum, Dacu...

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Detalles Bibliográficos
Autores principales: Muppalaneni, Naresh Babu, Rao, Allam Appa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524943/
https://www.ncbi.nlm.nih.gov/pubmed/23275691
http://dx.doi.org/10.6026/97320630008980