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Testing groups of genomic locations for enrichment in disease loci using linkage scan data: A method for hypothesis testing

Genes for complex disorders have proven hard to find using linkage analysis. The results rarely reach the desired level of significance and researchers often have failed to replicate positive findings. There is, however, a wealth of information from other scientific approaches which enables the form...

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Detalles Bibliográficos
Autores principales: Avramopoulos, Dimitrios, Zandi, Peter, Gherman, Adrian, Fallin, M Daniele, Bassett, Susan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525155/
https://www.ncbi.nlm.nih.gov/pubmed/16848972
http://dx.doi.org/10.1186/1479-7364-2-6-345