Genome-wide identification of genetic determinants for the cytotoxicity of perifosine

Perifosine belongs to the class of alkylphospholipid analogues, which act primarily at the cell membrane, thereby targeting signal transduction pathways. In phase I/II clinical trials, perifosine has induced tumour regression and caused disease stabilisation in a variety of tumour types. The genetic...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Liu, Wanqing, Poradosu, Enrique, Ratain, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525180/
https://www.ncbi.nlm.nih.gov/pubmed/19129090
http://dx.doi.org/10.1186/1479-7364-3-1-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525180/
https://www.ncbi.nlm.nih.gov/pubmed/19129090
http://dx.doi.org/10.1186/1479-7364-3-1-53

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