Hardy-Weinberg analysis of a large set of published association studies reveals genotyping error and a deficit of heterozygotes across multiple loci

In genetic association studies, deviation from Hardy-Weinberg equilibrium (HWD) can be due to recent admixture or selection at a locus, but is most commonly due to genotyping errors. In addition to its utility for identifying potential genotyping errors in individual studies, here we report that HWD...

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Detalles Bibliográficos
Autores principales: Sen, Srijan, Burmeister, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525187/
https://www.ncbi.nlm.nih.gov/pubmed/19129089
http://dx.doi.org/10.1186/1479-7364-3-1-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525187/
https://www.ncbi.nlm.nih.gov/pubmed/19129089
http://dx.doi.org/10.1186/1479-7364-3-1-36

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