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Recommendations for using standardised phenotypes in genetic association studies

Genetic association studies of complex traits often rely on standardised quantitative phenotypes, such as percentage of predicted forced expiratory volume and body mass index to measure an underlying trait of interest (eg lung function, obesity). These phenotypes are appealing because they provide a...

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Detalles Bibliográficos
Autores principales: Naylor, Melissa G, Weiss, Scott T, Lange, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525193/
https://www.ncbi.nlm.nih.gov/pubmed/19706362
http://dx.doi.org/10.1186/1479-7364-3-4-308