Neurofibromatosis type 1-associated tumours: Their somatic mutational spectrum and pathogenesis

Somatic gene mutations constitute key events in the malignant transformation of human cells. Somatic mutation can either actively speed up the growth of tumour cells or relax the growth constraints normally imposed upon them, thereby conferring a selective (proliferative) advantage at the cellular l...

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Detalles Bibliográficos
Autores principales: Spyk, Sebastian Laycock-van, Thomas, Nick, Cooper, David N, Upadhyaya, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525246/
https://www.ncbi.nlm.nih.gov/pubmed/22155606
http://dx.doi.org/10.1186/1479-7364-5-6-623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525246/
https://www.ncbi.nlm.nih.gov/pubmed/22155606
http://dx.doi.org/10.1186/1479-7364-5-6-623

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