Cargando…
Neurofibromatosis type 1-associated tumours: Their somatic mutational spectrum and pathogenesis
Somatic gene mutations constitute key events in the malignant transformation of human cells. Somatic mutation can either actively speed up the growth of tumour cells or relax the growth constraints normally imposed upon them, thereby conferring a selective (proliferative) advantage at the cellular l...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525246/ https://www.ncbi.nlm.nih.gov/pubmed/22155606 http://dx.doi.org/10.1186/1479-7364-5-6-623 |