Comparative Analysis of DNA Nanoparticles and AAVs for Ocular Gene Delivery

Gene therapy is a critical tool for the treatment of monogenic retinal diseases. However, the limited vector capacity of the current benchmark delivery strategy, adeno-associated virus (AAV), makes development of larger capacity alternatives, such as compacted DNA nanoparticles (NPs), critical. Here...

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Detalles Bibliográficos
Autores principales: Han, Zongchao, Conley, Shannon M., Makkia, Rasha, Guo, Junjing, Cooper, Mark J., Naash, Muna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525534/
https://www.ncbi.nlm.nih.gov/pubmed/23272225
http://dx.doi.org/10.1371/journal.pone.0052189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525534/
https://www.ncbi.nlm.nih.gov/pubmed/23272225
http://dx.doi.org/10.1371/journal.pone.0052189

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