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Adoptive Infusion of Tolerogenic Dendritic Cells Prolongs the Survival of Pancreatic Islet Allografts: A Systematic Review of 13 Mouse and Rat Studies

OBJECTIVE: The first Phase I study of autologous tolerogenic dendritic cells (Tol-DCs) in Type 1 diabetes (T1D) patients was recently completed. Pancreatic islet transplantation is an effective therapy for T1D, and infusion of Tol-DCs can control diabetes development while promoting graft survival....

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Detalles Bibliográficos
Autores principales: Sun, Guixiang, Shan, Juan, Li, Youping, Zhou, Yanni, Guo, Yingjia, Wu, Wenqiao, Yang, Tong, Xia, Mengjuan, Feng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525535/
https://www.ncbi.nlm.nih.gov/pubmed/23272217
http://dx.doi.org/10.1371/journal.pone.0052096