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Analysis of CPD Ultraviolet Lesion Bypass in Chicken DT40 Cells: Polymerase η and PCNA Ubiquitylation Play Identical Roles

Translesion synthesis (TLS) provides a mechanism of copying damaged templates during DNA replication. This potentially mutagenic process may operate either at the replication fork or at post-replicative gaps. We used the example of T-T cyclobutane pyrimidine dimer (CPD) bypass to determine the influ...

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Detalles Bibliográficos
Autores principales: Varga, Ágnes, Marcus, Adam P., Himoto, Masayuki, Iwai, Shigenori, Szüts, Dávid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525536/
https://www.ncbi.nlm.nih.gov/pubmed/23272247
http://dx.doi.org/10.1371/journal.pone.0052472