CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart

Natriuretic peptides (NPs) are cardioprotective through the activation of guanylyl cyclase (GC) receptors A and B. CD-NP, also known as cenderitide, is a novel engineered NP that was designed to uniquely serve as a first-in-class dual GC receptor agonist. Recognizing the aldosterone suppressing acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Fernando L., Sangaralingham, S. Jeson, Huntley, Brenda K., McKie, Paul M., Ichiki, Tomoko, Chen, Horng H., Korinek, Josef, Harders, Gerald E., Burnett, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525541/
https://www.ncbi.nlm.nih.gov/pubmed/23272242
http://dx.doi.org/10.1371/journal.pone.0052422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525541/
https://www.ncbi.nlm.nih.gov/pubmed/23272242
http://dx.doi.org/10.1371/journal.pone.0052422

Ejemplares similares