Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate

BACKGROUND: Tumor necrosis factor alpha (TNF) is able to kill cancer cells via receptor-mediated cell death requiring adenosine triphosphate (ATP). Clinical usage of TNF so far is largely limited by its profound hepatotoxicity. Recently, it was found in the murine system that specific protection of...

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Detalles Bibliográficos
Autores principales: Weiland, Timo, Klein, Kathrin, Zimmermann, Martina, Speicher, Tobias, Venturelli, Sascha, Berger, Alexander, Bantel, Heike, Königsrainer, Alfred, Schenk, Martin, Weiss, Thomas S., Wendel, Albrecht, Schwab, Matthias, Bitzer, Michael, Lauer, Ulrich M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525543/
https://www.ncbi.nlm.nih.gov/pubmed/23272249
http://dx.doi.org/10.1371/journal.pone.0052496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525543/
https://www.ncbi.nlm.nih.gov/pubmed/23272249
http://dx.doi.org/10.1371/journal.pone.0052496

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