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Translation Directed by Hepatitis A Virus IRES in the Absence of Active eIF4F Complex and eIF2

Translation directed by several picornavirus IRES elements can usually take place after cleavage of eIF4G by picornavirus proteases 2A(pro) or L(pro). The hepatitis A virus (HAV) IRES is thought to be an exception to this rule because it requires intact eIF4F complex for translation. In line with pr...

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Detalles Bibliográficos
Autores principales: Redondo, Natalia, Sanz, Miguel Angel, Steinberger, Jutta, Skern, Tim, Kusov, Yuri, Carrasco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525551/
https://www.ncbi.nlm.nih.gov/pubmed/23272212
http://dx.doi.org/10.1371/journal.pone.0052065