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25-Hydroxyvitamin D(3) and 1,25-Dihydroxyvitamin D(3) Promote the Differentiation of Human Subcutaneous Preadipocytes

1,25(OH)(2)D(3) inhibits adipogenesis in mouse 3T3-L1 adipocytes, but little is known about its effects or local metabolism in human adipose tissue. We showed that vitamin D receptor (VDR) and 1α-hydroxylase (CYP27B1), the enzyme that activates 25(OH)D(3) to 1,25(OH)(2)D(3), were expressed in human...

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Detalles Bibliográficos
Autores principales: Nimitphong, Hataikarn, Holick, Michael F., Fried, Susan K., Lee, Mi-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525569/
https://www.ncbi.nlm.nih.gov/pubmed/23272223
http://dx.doi.org/10.1371/journal.pone.0052171