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Role of the Beta Catenin Destruction Complex in Mediating Chemotherapy-Induced Senescence-Associated Secretory Phenotype

Cellular senescence is considered as a tumor suppressive mechanism. Recent evidence indicates however that senescent cells secrete various growth factors and cytokines, some of which may paradoxically promote cancer progression. This phenomenon termed senescence-associated secretory phenotype (SASP)...

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Detalles Bibliográficos
Autores principales: Basu, Dipanjan, Reyes-Mugica, Miguel, Rebbaa, Abdelhadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525570/
https://www.ncbi.nlm.nih.gov/pubmed/23272224
http://dx.doi.org/10.1371/journal.pone.0052188