Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

The ATM/ATR DNA damage checkpoint functions in the maintenance of genetic stability and some missense variants of the ATM gene have been shown to confer a moderate increased risk of prostate cancer. However, whether inactivation of this checkpoint contributes directly to prostate specific cancer pre...

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Detalles Bibliográficos
Autores principales: Chiu, Yung-Tuen, Liu, Ji, Tang, Kaidun, Wong, Yong-Chuan, Khanna, Kum Kum, Ling, Ming-Tat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525593/
https://www.ncbi.nlm.nih.gov/pubmed/23272087
http://dx.doi.org/10.1371/journal.pone.0051108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525593/
https://www.ncbi.nlm.nih.gov/pubmed/23272087
http://dx.doi.org/10.1371/journal.pone.0051108

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