Next-generation sequencing identified new oncogenes and tumor suppressor genes in human hepatic tumors

Genetic studies were performed in a French series of hepatocellular carcinomas. New oncogenes (NFE2L2) and tumor suppressor genes (IRF2, ARID1A and RPS6K3) were found to be recurrently altered. Moreover, a genotoxic signature was identified, raising the possible implication of a genotoxic exposure i...

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Detalles Bibliográficos
Autores principales: Amaddeo, Giuliana, Guichard, Cécile, Imbeaud, Sandrine, Zucman-Rossi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525620/
https://www.ncbi.nlm.nih.gov/pubmed/23264911
http://dx.doi.org/10.4161/onci.21480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525620/
https://www.ncbi.nlm.nih.gov/pubmed/23264911
http://dx.doi.org/10.4161/onci.21480

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