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Trogocytosis generates acquired regulatory T cells adding further complexity to the dysfunctional immune response in multiple myeloma
Trogocytosis, which results in the acquisition of myeloma cell-derived membrane proteins by T cells, and hence generates novel regulatory T cells, adds to the growing list of immune defects of multiple myeloma patients. The increasing complexity of the cancer-associated immune defects must be attent...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525637/ https://www.ncbi.nlm.nih.gov/pubmed/23264928 http://dx.doi.org/10.4161/onci.22032 |