How imiquimod licenses plasmacytoid dendritic cells to kill tumors

We have provided evidence for a multifaceted antitumor-function of the Toll-like receptor 7 (TLR7) agonist imiquimod, which rapidly recruits plasmacytoid dendritic cells and possibly other immune cells into tumors by inducing the secretion of CCL2 by dermal cells. Imiquimod induces pDC maturation an...

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Detalles Bibliográficos
Autores principales: Holcmann, Martin, Drobits, Barbara, Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525638/
https://www.ncbi.nlm.nih.gov/pubmed/23264929
http://dx.doi.org/10.4161/onci.22033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525638/
https://www.ncbi.nlm.nih.gov/pubmed/23264929
http://dx.doi.org/10.4161/onci.22033

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