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How imiquimod licenses plasmacytoid dendritic cells to kill tumors

We have provided evidence for a multifaceted antitumor-function of the Toll-like receptor 7 (TLR7) agonist imiquimod, which rapidly recruits plasmacytoid dendritic cells and possibly other immune cells into tumors by inducing the secretion of CCL2 by dermal cells. Imiquimod induces pDC maturation an...

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Detalles Bibliográficos
Autores principales:	Holcmann, Martin, Drobits, Barbara, Sibilia, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525638/ https://www.ncbi.nlm.nih.gov/pubmed/23264929 http://dx.doi.org/10.4161/onci.22033

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