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Dexamethasone Reduces Sensitivity to Cisplatin by Blunting p53-Dependent Cellular Senescence in Non-Small Cell Lung Cancer
INTRODUCTION: Dexamethasone (DEX) co-treatment has proved beneficial in NSCLC patients, improving clinical symptoms by the reduction of side effects after chemotherapy. However, recent studies have shown that DEX could render cancer cells more insensitive to cytotoxic drug therapy, but it is not kno...
| Autores principales: | , , , , , , , , , |
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| 格式: | Online Artículo Texto |
| 語言: | English |
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Public Library of Science
2012
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| 主題: | |
| 在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525662/ https://www.ncbi.nlm.nih.gov/pubmed/23272171 http://dx.doi.org/10.1371/journal.pone.0051821 |