Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells

Rho signaling is increasingly recognized to contribute to invasion and metastasis. In this study, we discovered that metastasis-associated protein S100A4 interacts with the Rho binding domain (RBD) of Rhotekin, thus connecting S100A4 to the Rho pathway. GST pull-down and immunoprecipitation assays d...

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Detalles Bibliográficos
Autores principales: Chen, Min, Bresnick, Anne R., O’Connor, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525797/
https://www.ncbi.nlm.nih.gov/pubmed/22964635
http://dx.doi.org/10.1038/onc.2012.383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525797/
https://www.ncbi.nlm.nih.gov/pubmed/22964635
http://dx.doi.org/10.1038/onc.2012.383

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