Viral Dose, Radioiodine Uptake, and Delayed Efflux in Adenovirus Mediated NIS Radiovirotherapy Correlates with Treatment Efficacy

We have constructed a prostate tumor specific conditionally replicating adenovirus (CRAd), named Ad5PB_RSV-NIS that expresses the human sodium iodine symporter gene (hNIS). LNCaP tumors were established in nude mice and infected with this CRAd to study tumor viral spread, NIS expression, and efficac...

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Detalles Bibliográficos
Autores principales: Trujillo, Miguel A., Oneal, Michael J., McDonough, Samantha, Morris, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525803/
https://www.ncbi.nlm.nih.gov/pubmed/22972493
http://dx.doi.org/10.1038/gt.2012.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525803/
https://www.ncbi.nlm.nih.gov/pubmed/22972493
http://dx.doi.org/10.1038/gt.2012.71

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