Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways

BACKGROUND AND PURPOSE: Pyrazole derivatives have recently been suggested as selective blockers of transient receptor potential cation (TRPC) channels but their ability to distinguish between the TRPC and Orai pore complexes is ill-defined. This study was designed to characterize a series of pyrazol...

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Detalles Bibliográficos
Autores principales: Schleifer, H, Doleschal, B, Lichtenegger, M, Oppenrieder, R, Derler, I, Frischauf, I, Glasnov, TN, Kappe, CO, Romanin, C, Groschner, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525873/
https://www.ncbi.nlm.nih.gov/pubmed/22862290
http://dx.doi.org/10.1111/j.1476-5381.2012.02126.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525873/
https://www.ncbi.nlm.nih.gov/pubmed/22862290
http://dx.doi.org/10.1111/j.1476-5381.2012.02126.x

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